微流控SERS芯片及其生物传感应用

王志乐; 王著元; 宗慎飞; 崔一平

doi:10.3788/CO.20181103.0513

Volume 11 Issue 3

Jun. 2018

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Article Contents

Chinese Optics > 2018 > 11(3): 513-530.

WANG Zhi-le, WANG Zhu-yuan, ZONG Shen-fei, CUI Yi-ping. Microfluidic SERS chip and its biosensing applications[J]. Chinese Optics, 2018, 11(3): 513-530. doi: 10.3788/CO.20181103.0513

Citation:

WANG Zhi-le, WANG Zhu-yuan, ZONG Shen-fei, CUI Yi-ping. Microfluidic SERS chip and its biosensing applications[J]. Chinese Optics, 2018, 11(3): 513-530. doi: 10.3788/CO.20181103.0513

WANG Zhi-le, WANG Zhu-yuan, ZONG Shen-fei, CUI Yi-ping. Microfluidic SERS chip and its biosensing applications[J]. Chinese Optics, 2018, 11(3): 513-530. doi: 10.3788/CO.20181103.0513

Citation:

WANG Zhi-le, WANG Zhu-yuan, ZONG Shen-fei, CUI Yi-ping. Microfluidic SERS chip and its biosensing applications[J]. Chinese Optics, 2018, 11(3): 513-530. doi: 10.3788/CO.20181103.0513

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Microfluidic SERS chip and its biosensing applications

doi: 10.3788/CO.20181103.0513

Advanced Photonic Center, Southeast University, Nanjing 210096, China

Funds:

the Natural Science Foundation of China 61535003

the National Key Basic Research Program of China 2015CB352002

More Information

Corresponding author: WANG Zhu-yuan, E-mail:wangzy@seu.edu.cn; CUI Yi-ping, E-mail:cyp@seu.edu.cn
Received Date: 03 Jan 2018
Rev Recd Date: 29 Jan 2018
Publish Date: 01 Jun 2018

Abstract

Abstract

With excellent integrability and flexible operability, microfluidic chips have been developed rapidly. Among them, Surface-enhanced Raman Spectroscopy (SERS) has become a widely used detection technique due to its ultrasensitivity, unique fingerprint spectrum and narrow spectroscopic bands. The SERS microfluidic chip integrates the advantages of the SERS detection technology and the microfluidic chip. On the one hand, it provides an efficient platform for the repeatability and reliability of the SERS detection method. On the other hand, it promotes function expansion for microfluidic chips. The SERS microfluidic chips have broad application prospects in the fields of biomolecule detection, cell capture and even tissue simulation. In this review, the principle of SERS is briefly introduced, and the construction of SERS microfluidic chip and its applications in biosensing and detection are emphatically summarized. Finally, the problems and development direction of the research are proposed.
- surface-enhanced raman spectroscopy,
- microfluidic,
- SERS microfluidic chip,
- biosensing

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References(70)

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